Table 1 Distribution of Pfmdr1 single nucleotide polymorphisms in Tanzania
Regions | Pfmdr1 polymorphisms | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | N86Y | Y184F | D1246Y | |||||||||
| Â | N | Y | N/Y | Y | Y | F | Y/F | F | D | Y | D/Y | Y |
n (%) | n (%) | n (%) | Prevalence (%) | n (%) | n (%) | n (%) | Prevalence (%) | n (%) | n (%) | n (%) | Prevalence (%) | |
Tanga | 36 (38.3) | 56 (59.6) | 2 (2.1) | 58 (60.4) | 32 (34.8) | 60 (65.2) | 0 (0) | 60 (65.2) | 45 (52.9) | 39 (45.9) | 1 (1.2) | 40 (46.5) |
Coastal | 93 (72.1) | 33 (25.6) | 3 (2.3) | 36 (27.3) | 85 (63.0) | 50 (37.0) | 0 (0) | 50 (37.0) | 134 (93.7) | 7 (4.9) | 2 (1.4) | 9 (6.2) |
Mtwara | 49 (74.2) | 16 (24.2) | 1 (1.5) | 17 (25.4) | 43 (64.2) | 23 (34.3) | 1 (1.5) | 24 (35.3) | 55 (78.6) | 15 (21.4) | 0 (0) | 15 (21.4) |
Kagera | 90 (72.0) | 31 (24.8) | 4 (3.2) | 35 (27.1) | 82 (67.8) | 38 (31.4) | 1 (0.8) | 39 (32.6) | 112 (88.2) | 13 (10.2) | 2 (1.6) | 15 (11.6) |
Mbeya | 129 (95.6) | 4 (3.0) | 2 (1.5) | 6 (4.4) | 111 (88.0) | 13 (10.3) | 2 (1.6) | 15 (11.7) | 119 (89.5) | 13 (9.8) | 1 (0.8) | 14 (10.4) |
Mwanza | 72 (77.1) | 23 (22.9) | 0 (0) | 23 (24.2) | 64 (64.0) | 35 (35.0) | 1 (1.0) | 36 (35.6) | 73 (83.0) | 15 (17.0) | 0 (0) | 15 (23.6) |
Total | 469 (72.8) | 163 (25.3) | 12 (1.8) | Â | 417 (65) | 219 (34.2) | 5 (0.7) | Â | 538 (83) | 102 (15.7) | 6 (0.9) | Â |