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Figure 1 | Malaria Journal

Figure 1

From: Magnetic resonance imaging during life: the key to unlock cerebral malaria pathogenesis?

Figure 1

CT scans of adult CM patients from India showing mild to severe brain swelling. Non-enhanced 8 mm transverse sections of a control patient (A) and two acute CM patients showing mild and severe cerebral oedema (B and C, respectively). Images were obtained within 6 hours of admission at Ispat General Hospital in Rourkela, Orissa, India, as part of another study [52] and using a Philips W1000 third generation CT scan. Brain swelling observed in (B) and (C) was defined as loss of cerebrospinal fluid space, small ventricles, absence of sulci, and/or compression of the cisterns. Mild brain swelling was defined as local or diffuse effacement of sulci and Sylvian fissure without compression of the supratentorial ventricular system (B). Severe swelling was defined as diffuse obliteration of sulci, Sylvian fissure and basal cisterns, together with an important mass effect causing near total obliteration of the supratentorial ventricular system and generalized hypodensity of brain parenchyma (C).

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