From: Declining efficacy of artesunate plus sulphadoxine-pyrimethamine in northeastern India
Study site | Lunglei (Mizoram) | Gomati (Tripura) | Changlang (Arunachal Pradesh) |
---|---|---|---|
Characteristic | (N = 66) | (N = 72) | (N = 37) |
Sex (no (%)) | |||
Male | 39 (59.1) | 39 (54.2) | 22 (59.5) |
Female | 27 (40.9) | 33 (45.8) | 15 (40.5) |
Age category (no (%)) | |||
< 5 yr | 6 (9.1) | 24 (33.3) | 7 (18.9) |
5-15 yr | 26 (39.4) | 30 (41.7) | 18 (48.6) |
Adult | 34 (51.5) | 18 (25.0) | 12 (32.4) |
Temperature (˚C) | |||
Mean ± SD | 36.3 ± 1.3 | 38.1 ± 0.4 | 38.2 ± 0.5 |
Range | 36.2-39.3 | 37.5 - 39.2 | (37.5 - 39.1) |
Febrile (≥ 37.5) | |||
Yes (no (%)) | 13 (19.7) | 72 (100.0) | 37 (100.0) |
No (no (%)) | 53 (80.3) | - | - |
Parasite count (no/μl)a | |||
Mean ± SD | 18899.3 ± 23979.5 | 18507.6 ± 20937.3 | 31186.5 ± 27451.6 |
< 5,000 | 22 (33.3) | 26 (36.1) | 7 (18.9) |
5,000-50,000 | 36 (54.5) | 37 (51.4) | 20 (54.1) |
≥ 50,000 | 8 (12.1) | 9 (12.5) | 10 (27.0) |
Gametocytes on day 0 | |||
(no (%)) | 3 (4.2) | 17 (23.9) | 12 (32.4) |
Number of mutations | |||
0-2 | 6 (9.1) | 3 (4.2) | 1 (2.7) |
2-4 | 4 (6.1) | 5 (6.9) | 2 (5.4) |
≥ 5 | 56 (84.8) | 64 (88.9) | 34 (91.9) |