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Figure 1 | Malaria Journal

Figure 1

From: Reduced ADAMTS13 activity is associated with an ADAMTS13 SNP, fever and microparticles in a malaria-like model

Figure 1

Genotypic association of rs4962153 genotype and ADAMTS13 antigen and activity. (A) The mean of ADAMTS13 antigen levels in participants with AA, AG and GG genotype of rs4962153 were 683.91, 568.02 and 327.26 ng/ml, respectively. ADAMTS13 antigen levels in participants with AA genotype were significantly reduced compared to both of AG and GG genotype (P < 0.05 and < 0.001, respectively). Furthermore, ADAMTS13 antigen in participants with AG genotype was also significantly decreased when compared to GG genotype (P < 0.05). (B) ADAMTS13 activity levels in participants with AA genotype (mean = 58.26%), were significantly reduced when compared to AG genotype (mean = 84.78%; P < 0.05) and GG genotype (mean = 95.53%; P < 0.001). The middle line referred mean of each individual genotype. *P < 0.05, **P < 0.01, ***P < 0.001.

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Malaria Journal

ISSN: 1475-2875

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