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Table 1 Comparison of sensitivity and specificity of gametocyte detection between light microscopy (LM), magnetic fractionation (MF) and reverse transcriptase polymerase chain reaction (RTPCR)

From: Comparison of three methods for detection of gametocytes in Melanesian children treated for uncomplicated malaria

A1

LM

Total

A2

Reference

 

0

1

  

LM

MF

MF

0

266

1

267

Sensitivity

0.99

0.39

1

136

88

224

Specificity

0.66

0.99

Total

402

89

491

   

B1

LM

Total

B2

Reference

 

0

1

  

LM

RTPCR

RTPCR

0

110

3

113

Sensitivity

0.94

0.40

1

75

50

125

Specificity

0.59

0.97

Total

185

53

238

   

C1

RTPCR

Total

C2

Reference

 

0

1

  

RTPCR

MF

MF

0

89

34

123

Sensitivity

0.74

0.77

1

29

99

128

Specificity

0.75

0.72

Total

118

133

251

   
  1. In each of the three comparisons (A: LM vs MF; B: LM vs RTPCR and C: RTPCR vs MF) both methods served as reference standard.