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Table 1 Baseline demographics and hematological parameters of the study groups

From: Tumour necrosis factor, interleukin-6 and interleukin-10 are possibly involved in Plasmodium vivax-associated thrombocytopaenia in southern Pakistani population

 

Healthy Controls (HC)

Malaria cases (thrombocytopaenia)

P value

Mild (MI)

Moderate (M)

Profound (P)

M vs P

N

100

10

93

79

 

Haemoglobin

12.29 ± 1.99

12.38 ± 1.80

12.65 ± 1.63

11.68 ± 2.19

0.002*

RBC

4.38 ± 0.43

4.46 ± 0.69

4.39 ± 0.50

4.05 ± 0.70

0.000*

WBC

5.94 ± 2.43

7.05 ± 2.31

5.99 ± 2.72

5.8 ± 3.11

0.658

Neutrophils

63.5 ± 15

59.38 ± 12.3

72.0 ± 13.78

68.44 ± 14.2

0.098

Lymphocytes

21.7 ± 11.4

26.56 ± 9.93

19.25 ± 11.16

22.27 ± 11.19

0.079

Eosinophils

0.97 ± 1.16

0.66 ± 0.55

0.82 ± 1.22

0.92 ± 0.96

0.554

Monocytes

8.98 ± 5.07

12.94 ± 3.24

7.62 ± 4.6

8.28 ± 5.42

0.387

Platelets

175 ± 45.78

102.60 ± 32.97

74.76 ± 27.1

32.17 ± 11.19

0.000*

  1. Values represent medians ± standard deviation.
  2. Reference units used:
  3. Haemoglobin = gm/dl; RBC = 1012/L; WBC = 106/L; Platelets = 109/L.
  4. Neutrophils, lymphocytes, eosinophils, monocytes =%.
  5. * = singificant (p-value <0.05).