Figure 2

Alignment of central tandem repeat region between amino acid positions 88 and 105 in the pvdhfr gene and frequencies of central tandem repeat types circulating from Xishuangbanna and Bozhou. A) Sequences were constructed to the published amino acid sequences (accession no. X98123). Dots (. . . .) and dashes (---) represent identical residues and deletions, respectively. Amino acid changes resulting from nucleotide substitutions are shown in bold. B) Frequencies of four central tandem repeat types obtained from 53 P. vivax Xishuangbanna isolates (black) and 61 Bozhou isolates (grey).