Figure 2

TLR-dependence of cytokine production during Plasmodium berghei infection. (A, B) Levels of IFNG, IL6, IL4, TNF, MIP1B, and IL10 were measured by cytometric bead array in plasma collected from mice of the indicated genotypes three days (A) or six days (B) after infection with 10⁶P. berghei-infected erythrocytes. All units are pg/mL. Means with SE are shown. *, p < 0.05 (Mann-Whitney) (n = 30 B6, n = 22 Tlr7^-/-, n = 11 Tlr9^−/−, n = 3 Tlr7^-/-Tlr9^-/-, n = 15 Myd88^−/−). Data were pooled from three independent experiments.