Figure 2

Multivariate analysis estimating late severe anaemia occurrence risk among patients who participated to all haemoglobin evaluation from day 0, 7, 14, and 28. n = 1,053, 956 and 941, respectively, for patients who participated to severe anaemia evaluation from day 7 to day 28, day 14 to day 28, and day 28. AL, artemether-lumefantrine; AS-AQ/AS-SP, artesunate plus amodiaquine/artesunate plus sulphadoxine-pyrimethamine; AS, artesunate; <5 years, <5 years old; PfDay0, Log Plasmodium falciparum density on day 0; TreatFail, Treatment failure outcome. Odds ratio were obtained from generalized linear and latent mixed model with binomial family using site as random effect; Covariates references were: CQ, AQ and SP for treatment, the age ≥5 years old for the age group, the 28-day cured parasite outcome after treatment for the treatment failure outcome, the baseline parasite density was log transformed and treated as continuous variable.