Table 1 Covariates assessed in the pharmacokinetic analysis
Covariate (unit) | Type |
|---|---|
Actual dose (mg) | Continuous |
Study (1 or 2) | Categorical |
Age (years) | Continuous |
Gender | Categorical |
Race | Categorical |
Weight at baseline (kg) | Continuous |
Height (cm) | Continuous |
Body surface area at baseline (m2) | Continuous |
Body mass index at baseline (kg/m2) | Continuous |
Ideal body weight at baseline (kg) | Continuous |
Lean body weight at baseline (kg) | Continuous |
Aspartate aminotransferase at baseline (U/L) | Continuous |
Alanine aminotransferase at baseline (U/L) | Continuous |
Bilirubin at baseline (mg/dL) | Continuous |
Albumin at baseline (g/dL) | Continuous |
Calculated creatinine clearance at baseline (mL/min) | Continuous |