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Table 1 Admission characteristics of sickle cell disease (SCD) or non-SCD (HbAA) subjects with uncomplicated malaria

From: A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine in Ghanaian paediatric sickle cell and non-sickle cell disease patients with acute uncomplicated malaria

 

SCD (n = 60)

HbAA (n = 59)

p

Age* (years)

7.92 (6.98-9.98)

5.45 (4.67-6.35)

0.001

Weight (kg)

23.18 (19.11)

20.54 (8.34)

0.077

Temperature (°C)

37.90 (1.12)

38.62 (1.12)

0.001

Jaundice (n)

42 (79.2 %)

4 (6.7 %)

< 0.001

Spleen size (cm)

1.27 (2.73)

0.20 (0.81)

0.008

Liver size (cm)

3.42 (4.70)

0.43 (1.32)

< 0.001

Parasite density* (/μL)

1,197 (645-2221)

11,774 (5256-26375)

0.0006

Haemoglobin (g/dL)

6.56 (2.22)

9.71 (2.16)

<0.0001

WBC (109/L)

23.95 (18.45)

10.21 (5.92)

<0.0001

Platelet count (109/L)

254.8 (133.9)

154.9 (106.1)

<0.0002

  1. Data are means (SD), except *geometric mean (95% CI), SCD = sickle cell disease; HbAA = non-SCD.