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Table 1 Admission characteristics of sickle cell disease (SCD) or non-SCD (HbAA) subjects with uncomplicated malaria

From: A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine in Ghanaian paediatric sickle cell and non-sickle cell disease patients with acute uncomplicated malaria

  SCD (n = 60) HbAA (n = 59) p
Age* (years) 7.92 (6.98-9.98) 5.45 (4.67-6.35) 0.001
Weight (kg) 23.18 (19.11) 20.54 (8.34) 0.077
Temperature (°C) 37.90 (1.12) 38.62 (1.12) 0.001
Jaundice (n) 42 (79.2 %) 4 (6.7 %) < 0.001
Spleen size (cm) 1.27 (2.73) 0.20 (0.81) 0.008
Liver size (cm) 3.42 (4.70) 0.43 (1.32) < 0.001
Parasite density* (/μL) 1,197 (645-2221) 11,774 (5256-26375) 0.0006
Haemoglobin (g/dL) 6.56 (2.22) 9.71 (2.16) <0.0001
WBC (109/L) 23.95 (18.45) 10.21 (5.92) <0.0001
Platelet count (109/L) 254.8 (133.9) 154.9 (106.1) <0.0002
  1. Data are means (SD), except *geometric mean (95% CI), SCD = sickle cell disease; HbAA = non-SCD.
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Malaria Journal

ISSN: 1475-2875

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