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Table 2 Admission characteristics of sickle cell disease (SCD) subjects with malaria versus that of SCD subjects in steady state

From: A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine in Ghanaian paediatric sickle cell and non-sickle cell disease patients with acute uncomplicated malaria

  SCD-malaria (n = 60) SCD Steady state (n = 82) p
Age* (years) 7.92 (6.98-9.98) 6.86 (6.15-7.65) 0.072
Weight (kg) 23.18 (19.11) - -
Temperature (°C) 37.90 (1.12) - -
Jaundice (n) 42 (79.2 %) - -
Spleen size (cm) 1.27 (2.73) - -
Liver size (cm) 3.42 (4.70) - -
Parasite density* (/μL) 1,197 (645-2,221) - -
Haemoglobin (g/dL) 6.56 (2.22) 8.14 (1.59) <0.0001
WBC (109/L) 23.95 (18.45) 13.76 (4.34) <0.0001
Platelet count (109/L) 254.8 (133.9) 413.122 (184.38) <0.0001
  1. Data are means (SD), except *geometric mean (95% CI), SCD = sickle cell disease; SCD Steady state = sickle cell disease (malaria-negative) subjects in steady state.