|
SCD-malaria (n = 60)
|
SCD Steady state (n = 82)
|
p
|
---|
Age* (years)
|
7.92 (6.98-9.98)
|
6.86 (6.15-7.65)
|
0.072
|
Weight (kg)
|
23.18 (19.11)
|
-
|
-
|
Temperature (°C)
|
37.90 (1.12)
|
-
|
-
|
Jaundice (n)
|
42 (79.2 %)
|
-
|
-
|
Spleen size (cm)
|
1.27 (2.73)
|
-
|
-
|
Liver size (cm)
|
3.42 (4.70)
|
-
|
-
|
Parasite density* (/μL)
|
1,197 (645-2,221)
|
-
|
-
|
Haemoglobin (g/dL)
|
6.56 (2.22)
|
8.14 (1.59)
|
<0.0001
|
WBC (109/L)
|
23.95 (18.45)
|
13.76 (4.34)
|
<0.0001
|
Platelet count (109/L)
|
254.8 (133.9)
|
413.122 (184.38)
|
<0.0001
|
- Data are means (SD), except *geometric mean (95% CI), SCD = sickle cell disease; SCD Steady state = sickle cell disease (malaria-negative) subjects in steady state.