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Table 2 Admission characteristics of sickle cell disease (SCD) subjects with malaria versus that of SCD subjects in steady state

From: A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine in Ghanaian paediatric sickle cell and non-sickle cell disease patients with acute uncomplicated malaria

 

SCD-malaria (n = 60)

SCD Steady state (n = 82)

p

Age* (years)

7.92 (6.98-9.98)

6.86 (6.15-7.65)

0.072

Weight (kg)

23.18 (19.11)

-

-

Temperature (°C)

37.90 (1.12)

-

-

Jaundice (n)

42 (79.2 %)

-

-

Spleen size (cm)

1.27 (2.73)

-

-

Liver size (cm)

3.42 (4.70)

-

-

Parasite density* (/μL)

1,197 (645-2,221)

-

-

Haemoglobin (g/dL)

6.56 (2.22)

8.14 (1.59)

<0.0001

WBC (109/L)

23.95 (18.45)

13.76 (4.34)

<0.0001

Platelet count (109/L)

254.8 (133.9)

413.122 (184.38)

<0.0001

  1. Data are means (SD), except *geometric mean (95% CI), SCD = sickle cell disease; SCD Steady state = sickle cell disease (malaria-negative) subjects in steady state.
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Malaria Journal

ISSN: 1475-2875

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