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Table 3 Frequency of presenting symptoms and signs among sickle cell disease (SCD) and non-SCD (HbAA) children with uncomplicated malaria

From: A randomized trial of artesunate-amodiaquine versus artemether-lumefantrine in Ghanaian paediatric sickle cell and non-sickle cell disease patients with acute uncomplicated malaria

Symptom/sign

SCD (n = 60)

Symptom/sign

HbAA (n = 59)

Fever*

33

Fever

57

Bone and/or joint pain

24

Vomiting

32

Abdominal pain

11

Headache

21

Headache

10

Abdominal pain

17

Chills and/or rigors

9

Poor appetite

11

Jaundice

7

Cough

6

General malaise

5

General malaise

4

Vomiting

4

Convulsion

3

Dark urine

4

Nasal congestion

2

Poor appetite

3

Chills and/or rigors

1

Cough

3

Diarrhoea

1

Dizziness

2

Dizziness

1

Easy fatigability

2

Weight loss

1

Sore throat

1

-

 

Nasal congestion

1

-

 

Priapism

1

-

 

Swollen lower limb

1

-

 
  1. *Fever = measured temperature ≥ 37.5°C; majority of subjects presented with more than one symptom; therefore, data is not 100% cumulative.