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Table 1 Genotyping of pfcrt , pfmdr1 , pfdhfr and pfdhps in P. falciparum from Brazil, according to two distinct therapeutic regimen periods

From: Analysis of polymorphisms in Plasmodium falciparum genes related to drug resistance: a survey over four decades under different treatment policies in Brazil

Period

pfcrt

pfmdr1

pfdhfr

pfdhps

 

76

86

1246

Copy number

51

59

108

437

540

 

T (%)

Y (%)

Y (%)

1 (%)

>1 (%)

I (%)

N + I (%)

R (%)

C + R (%)

N (%)

G (%)

E (%)

K + E (%)

1

100

1.5

100

62.7

37.3

100

0

0

0

100

100

93.7

1.5

2

100

25

100

58

42

81.2

18.7

6.4

16.1

100

100

75

0