| |
P. vivax/P. cynomolgi
|
P. vivax/P. knowlesi
|
|---|
|
Worldwide isolates
|
Fixed
|
Polymorphic
|
NI (p-values)
|
Fixed
|
Polymorphic
|
NI (p-values)
|
|---|
|
Non-synonymous substitutions
|
45.62
|
11
|
4.45 (0.003)
|
61.95
|
11
|
4.12 (0.004)
|
|
Synonymous substitutions
|
110.71
|
6
|
138.81
|
6
|
|
Colombian isolates
| | | | | | |
|
Non-synonymous substitutions
|
46.69
|
8
|
9.65 (0.000)
|
63.06
|
8
|
8.80 (0.001)
|
|
Synonymous substitutions
|
112.65
|
2
|
138.81
|
2
|
- The McDonald-Kreitman test involved using the sequences obtained from the databases together with the Colombian ones (worldwide isolates), and just those obtained in the Colombian population (Colombian isolates). The data regarding divergence between species was obtained by comparing P. vivax sequences to that from two related species: P. cynomolgi and P. knowlesi. NI: neutral index.
