Global and local genetic diversity at two microsatellite loci in Plasmodium vivax parasites from Asia, Africa and South America

Table 1 Heterozygosity (He) at the two microsatellite loci m1501 and m3502 in every survey

	Study site	n	Year	n (%)	m1501	MOI	n (%)	m3502	MOI	m1501 + m3502	Ref
	Study site	n	Year	n (%)	He	MOI	n (%)	He	MOI	n(%)	Ref
Asia	Sri Lanka	386	2002-2006	352 (91.2)	0.85	1.276	357 (92.5)	0.74	1.073	338 (87.6)	*and [10]
	Nepal	55	2006, 2009-2010	53 (96.4)	0.94	1.189	49 (89.1)	0.80	1.347	47 (85.5)	*and [23]
	Pak/Afg	329	2001, 2003-2007	315 (95.7)	0.91	1.365	314 (95.4)	0.80	1.650	309309 (93.9)	*and [24, 25]
	Korea	58	1996-2000, 2007	58 (100)	0.42	---	58 (100)	0.73	---	58 (100)	[6]
	India	90	2003-2004	78 (86.7)	0.90	---	79 (87.8)	0.86	---	---	[17]
	Laos	81	2001-2003	81 (100)	0.83	---	74 (91.4)	0.90	---	74 (91.4)	[17]
	Thailand	92	1992-1998	91 (98.9)	0.89	---	91 (98.9)	0.85	---	---	[17]
	PNG	108	2004-2005	107 (99.1)	0.91	1.907	108 (100)	0.86	1.648	107 (99.1)	[18]
South A.	Columbia	82	2001-2003	80 (97.6)	0.70	---	82 (100)	0.76	---	80 (97.6)	[17]
	Venezuela	130	1996-1997	113 (86.9)	0.73	1.416	98 (75.4)	0.57	1.235	97 (74.6)	*
	Ecuador	17	2009	17 (100)	0.22	1.176	17 (100.0)	0.76	1.176	17 (100.0)	*
Africa	Sudan	8	2006	7 (87.5)	0.71	1.571	4 (50.0)	1.00	1.235	3 (37.5)	*
	São Tomé	4	2000	4 (100.0)	0.83	1.250	4 (100.0)	0.83	2.250	4 (100.0)	*
	n =	1440	1992-2010	1356 (94.2)		1.614	1335 (92.7)		1.490	1134/1258 (90.1)

PNG: Papua New Guinea. Pak/Afg: Pakistan/Afghanistan. South A: South America. The number (and percentage) of samples successfully amplified for each MS locus and for the two loci combined are shown in every survey. Multiplicty of infection (MOI) is calculated by averaging the number of alleles detected in the total number of PCR positive samples. Data not available are indicated by “---”. Reference marked as * is this study.

ISSN: 1475-2875