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Table 2 Comparison of histoscore variables and measures of villous architecture between different clinical groups

From: A morphometric and histological study of placental malaria shows significant changes to villous architecture in both Plasmodium falciparum and Plasmodium vivax infection

Variable Controls vs Treated malaria vs Active malaria P. falciparum vs P. vivax or Mixed Pf/Pv Subgroups of PCA patients – Treated Pf Early/Mid or late in gestation
HISTOSCORE    
Presence of parasitized erythrocytes <0.001** 1.000 N/A (all –ve)
Inflammation <0.001** 0.177 0.382
Pigment <0.001** 1.000 0.471
Parasitaemia 0.0001** 0.855 N/A (all –ve)
Inflammation score (I-III) 0.001** 0.346 0.481
Pigment score (I-III) 0.0002** 0.613 0.335
IMAGE ANALYSIS    
Villous area (mm2) 0.0084** 0.321 0.554
Villous vascularity 0.0139* 0.094 0.667
Villi/hpf 0.0001** 0.321 0.235
Perimeter/villous (mm) 0.0006** 0.629 0.203
Total perimeter mm/10 hpf 0.0004** 0.119 0.523
  1. Pf = P. falciparum, Pv = P. vivax, *P < 0.05, **P < 0.01 N/A = Not Applicable.