Variable | Controls vs Treated malaria vs Active malaria | P. falciparum vs P. vivax or Mixed Pf/Pv | Subgroups of PCA patients – Treated Pf Early/Mid or late in gestation |
---|---|---|---|
HISTOSCORE | Â | Â | Â |
Presence of parasitized erythrocytes | <0.001** | 1.000 | N/A (all –ve) |
Inflammation | <0.001** | 0.177 | 0.382 |
Pigment | <0.001** | 1.000 | 0.471 |
Parasitaemia | 0.0001** | 0.855 | N/A (all –ve) |
Inflammation score (I-III) | 0.001** | 0.346 | 0.481 |
Pigment score (I-III) | 0.0002** | 0.613 | 0.335 |
IMAGE ANALYSIS | Â | Â | Â |
Villous area (mm2) | 0.0084** | 0.321 | 0.554 |
Villous vascularity | 0.0139* | 0.094 | 0.667 |
Villi/hpf | 0.0001** | 0.321 | 0.235 |
Perimeter/villous (mm) | 0.0006** | 0.629 | 0.203 |
Total perimeter mm/10 hpf | 0.0004** | 0.119 | 0.523 |