Skip to main content

Table 2 Comparison of histoscore variables and measures of villous architecture between different clinical groups

From: A morphometric and histological study of placental malaria shows significant changes to villous architecture in both Plasmodium falciparum and Plasmodium vivax infection

Variable

Controls vs Treated malaria vs Active malaria

P. falciparum vs P. vivax or Mixed Pf/Pv

Subgroups of PCA patients – Treated Pf Early/Mid or late in gestation

HISTOSCORE

   

Presence of parasitized erythrocytes

<0.001**

1.000

N/A (all –ve)

Inflammation

<0.001**

0.177

0.382

Pigment

<0.001**

1.000

0.471

Parasitaemia

0.0001**

0.855

N/A (all –ve)

Inflammation score (I-III)

0.001**

0.346

0.481

Pigment score (I-III)

0.0002**

0.613

0.335

IMAGE ANALYSIS

   

Villous area (mm2)

0.0084**

0.321

0.554

Villous vascularity

0.0139*

0.094

0.667

Villi/hpf

0.0001**

0.321

0.235

Perimeter/villous (mm)

0.0006**

0.629

0.203

Total perimeter mm/10 hpf

0.0004**

0.119

0.523

  1. Pf = P. falciparum, Pv = P. vivax, *P < 0.05, **P < 0.01 N/A = Not Applicable.