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Table 4 P-values for differences in survival curves according to the treatment received

From: Enantiomerically pure amino-alcohol quinolines: in vitro anti-malarial activity in combination with dihydroartemisinin, cytotoxicity and in vivo efficacy in a Plasmodium berghei mouse model

  

( S)-pentyl

( S)-heptyl

Mefloquine

  

3 mg kg−1

9 mg kg−1

3 mg kg−1

9 mg kg−1

9 mg kg−1

Control

 

0.0059 a

0.0017

0.0094

0.0002

<0.0001

(S)-pentyl

3 mg kg−1

 

0.5691

0.6281

0.8383

0.564

9 mg kg−1

  

0.2959

0.2382

0.0071

(S)-heptyl

3 mg kg−1

   

0.8011

0.4406

9 mg kg−1

    

0.0599

  1. a:statistically significant values are indicated in bold characters.