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Table 2 Prevalence of IgG antibody responses against MSP1p19 and PF13 according to different formulations of ELISA and duplex MBA data

From: Comparative analysis of IgG responses to Plasmodium falciparum MSP1p19 and PF13-DBL1α1 using ELISA and a magnetic bead-based duplex assay (MAGPIX®-Luminex) in a Senegalese meso-endemic community

Villagers

Antibody responses to PF13

Antibody responses to PfMSP1p19

Age-class

No

OD-ratio*

%resp.

MFI-ratio*

%resp.

%ROC**

OD-ratio

%resp.

MFI-ratio

%resp.

%ROC

<5y

11

1.9

27%

2.3

18%

18%

3.7

64%

3.4

36%

36%

5-9y

39

6.0

51%

8.7

59%

54%

3.6

49%

3.7

33%

56%

10-14y

34

10.3

94%

12.5

71%

71%

5.1

74%

5.9

59%

74%

15-29y

65

9.4

74%

11.1

68%

68%

6.6

80%

6.5

57%

63%

≥30y

68

8.7

74%

8.6

72%

72%

7.5

85%

6.9

69%

79%

all

217

8.3

71%

9.7

65%

65%

5.9

74%

5.8

56%

67%

  1. *Mean values of antibody responses measured with ELISA and duplex magpix test.
  2. **Incidence of responders using optimal threshold defined by ROC analysis.