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Figure 3 | Malaria Journal

Figure 3

From: In vitro and in vivo anti-malarial activity of tigecycline, a glycylcycline antibiotic, in combination with chloroquine

Figure 3

Progress of parasitaemia in Plasmodium berghei -infected mice treated with [A] chloroquine (CQ); [B] tigecycline (TG) once daily dose; [C] tigecycline (TG) split dose; and, [D] combination of tigecycline (TG) and chloroquine (CQ). Each point represent value mean ± SD of five mice or the number of mice remaining live at that point of time. The numbers shown along each graph show the daily dose of the specified drug. The mice were treated daily with dose of the drug indicated, for four days staring from day 0 (within 1–2 hours after inoculating the mice with P. berghei parasitized erythrocytes. Additional details are described in Methods.

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Malaria Journal

ISSN: 1475-2875

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