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Table 4 Cross validation result summary for TK900D

From: The development and validation of an LC-MS/MS method for the determination of a new anti-malarial compound (TK900D) in human whole blood and its application to pharmacokinetic studies in mice

Species

Human

Mouse

Human

Mouse

Human

Mouse

Human

Mouse

Nominal conc. (ng/ml)

800.0

800.0

160.0

160.0

10.00

10.00

3.906

3.906

Mean (n = 6)

809.2

899.3

160.8

185.7

9.889

10.66

3.912

3.946

% CV

7.5

5.4

8.2

5.6

9.1

12.2

9.4

11.9

% Bias

1.2

12.4

0.5

16.1

-1.1

6.6

0.2

1.0