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Table 3 Allele frequency of CYP3A4*1B and CYP3A5*3 reported from previous studies in African populations

From: Cytochrome P450 single nucleotide polymorphisms in an indigenous Tanzanian population: a concern about the metabolism of artemisinin-based combinations

Country

Number of subjects

CYP3A4*1B (%)

CYP3A5*3 (%)

Senegal

178

79 [38]

-

Cameroon

72

78.0 [39]

-

East Africa

 

-

36 [40]

South Africa

980,987

73.0-76.0 [41, 42]

15.0 [41]

Ghana

129-204

72.0-81 [38, 43]

15.0 [43]

Mozambique

86

73.8 [44]

-

Sao Tomé and

78

67.7 [44]

-

Tanzania (Zanzibar)

99, 92

69.2 [45]

15.8 [45]

Tanzania (Mainland)

165

74 [29]

18 [29]

Guinea Bissau

 

74 [46]

-

Zimbabwe

100

-

77.6 [47]