Cytochrome P450 single nucleotide polymorphisms in an indigenous Tanzanian population: a concern about the metabolism of artemisinin-based combinations

Table 4 **Allele frequencies of CYP2C82, CYP2C83 and CYP2B6*6 reported from previous studies in African populations**

Country number	CYP2C82 (%)*	CYP2C83 (%)*	CYP2B66 (%)*
Burundi 60	-	-	50.0 [48]
Burkina Faso 275	15.5 [49]	0.3 [49]	-
Ghana 200	17-17.9 [50–52]	0 [50]	46.9 [22]
Zimbabwe 74	-	-	49 [53]
Mozambique 115	16.0 [54]	-	-
Senegal 88	22.0 [36]	-	-
Tanzania 165 (Zanzibar)	13.9 [55]	2.1 [55]	-
Tanzania 165 (Mainland)	-	-	34-41.8 [29, 56]
South Africa 182 (Xhosa)	-	-	32.14 [57]
Madagascar 153	15.0 [36]	-	-

ISSN: 1475-2875