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Table 4 Hypothetical vector control interventions

From: An agent-based model of the population dynamics of Anopheles gambiae

HVCI

Interpretation

Real-world mapping

L Entering

Imposes a one-time killing effect (a one-time hazard) when an egg enters the larva stage

LSM by insecticidal control

L Updating

Imposes an additional killing effect for a larva; the killing effect sustains every hour during the entire larval development stage (see Equations 2–5) until the larva enters the pupa stage or dies

LSM by biological control

BMS Foraging

Imposes an additional killing effect for a host seeking female mosquito in the BMS stage; the killing effect is in action whenever a female encounters a host (with P FindHost =25%) in BMS, and occurs over every hour until the mosquito successfully gets a blood meal (and then enters the BMD stage) or dies; may occur in multiple gonotrophic cycles

ITNs

BMS Foraging, K=0%

A special case of BMS Foraging with no killing effectiveness; simulates a continuous effect (with no additional killing) on a host seeking female during the entire BMS stage; may occur in multiple gonotrophic cycles

Untreated bed nets

BMD Resting

Imposes an additional killing effect for a female mosquito in the BMD stage, and the killing effect sustains every hour of the 1–2.5 days duration in BMD (see Equation 7) until the mosquito enters the G stage or dies; may occur in multiple gonotrophic cycles

IRS

G Foraging

Imposes an additional killing effect for a female mosquito in the G stage seeking an aquatic habitat for oviposition; the killing effect is in action whenever a female is seeking a habitat (with P FindHabitat =25%) in G, and occurs over every hour until it successfully finds a habitat or dies; may occur in multiple gonotrophic cycles

Lethal ovitraps

(IA, BMS, BMD, G) Entering

Imposes an additional killing effect (a one-time hazard) for female mosquitoes entering the IA, BMS, BMD, and G stages; may occur in multiple gonotrophic cycles during BMS, BMD, G

ATSB

(IA, BMS, BMD, G) Resting

Imposes an additional killing effect for female mosquitoes resting in the IA, BMS, BMD, and G stages; the killing effect occurs over every hour (when mosquitoes are resting) in all of these stages, and in multiple gonotrophic cycles during BMS, BMD, G

Sugar meal traps

  1. The first element of an HVCI denotes the life cycle stage (or in some cases, multiple stages, which are enclosed in parentheses). The second element denotes the activity of the mosquito agent in the corresponding stage(s) and appears as a subscript. Optionally, a third element may denote the intervention parameters of coverage (C) and/or killing (K). For each HVCI, its interpretation by the model is described in column 2, and possible mapping to its real-world counterpart is listed in column 3.