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Table 2 Correlations of total IgG and subclass IgG1-IgG4 responses against EBA175 and PfRh2

From: Subclass responses and their half-lives for antibodies against EBA175 and PfRh2 in naturally acquired immunity against Plasmodium falciparum malaria

Antigen-IgG

Spearman r

p-value

EBA175 Total IgG vs

  

IgG1

0.57

<0.0001

IgG2

0.46

<0.0001

IgG3

0.49

<0.0001

IgG4

0.38

<0.0001

EBA175 IgG1 vs

  

IgG2

0.5

<0.0001

IgG3

0.63

<0.0001

IgG4

0.25

<0.0001

EBA 175 IgG2 vs

  

IgG3

0.48

<0.0001

IgG4

0.40

<0.0001

EBA175 IgG3 vs

  

IgG4

0.34

<0.0001

Rh2 Total IgG vs

  

IgG1

0.55

<0.0001

IgG2

0.07

0.26

IgG3

0.04

0.48

IgG4

0.1

0.08

Rh2 IgG1 vs

  

IgG2

0.07

0.23

IgG3

0.09

0.13

IgG4

0.1

0.07

Rh2 IgG2 vs

  

IgG3

0.27

<0.0001

IgG4

0.21

0.004

Rh2 IgG3 vs

  

IgG4

-0.05

0.35