Study 1134 | Study 1155 | |||
---|---|---|---|---|
AZCQ 1,000 mg (N = 114) | MQ 1,250 mg (N = 115) | AZCQ 1,000 mg (N = 113) | MQ 1,250 mg (N = 116) | |
Sex, n | ||||
Male | 66 | 61 | 65 | 63 |
Female | 48 | 54 | 48 | 53 |
Age group, years, n | ||||
18-44 | 106 | 101 | 100a | 99 |
45-64 | 8 | 13 | 13 | 15 |
≥65 | 0 | 1 | 0 | 2 |
Mean (SD) | 29.4 (9.6) | 30.2 (11.0) | 30.2 (11.0) | 31.2 (12.4) |
Weight, kg | ||||
Mean (SD) | 61.4 (10.8) | 60.4 (11.0) | 60.0 (9.9) | 59.4 (10.1) |
Range | 40.0-105.0 | 39.0-107.0 | 40.0-83.6 | 39.0-94.0 |
Baseline parasite count/μL, mean ± SD | 20,889 ± 24,176 | 20,146 ± 27,564 | 16,686 ± 22,863 | 17,651 ± 22,435 |
Range | 160-111,040 | 1,040-164,600 | 120-93,440 | 1,000-97,234 |
Number of episodes of malaria in previous 2 years | ||||
0 | 61 | 66 | 69 | 67 |
1 | 20 | 18 | 9 | 14 |
2 | 15 | 9 | 16 | 18 |
≥3 | 17 | 22 | 19 | 17 |