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Table 1 Subject demographics

From: Efficacy and safety of a combination of azithromycin and chloroquine for the treatment of uncomplicated Plasmodium falciparum malaria in two multi-country randomised clinical trials in African adults

 

Study 1134

Study 1155

 

AZCQ 1,000 mg (N = 114)

MQ 1,250 mg (N = 115)

AZCQ 1,000 mg (N = 113)

MQ 1,250 mg (N = 116)

Sex, n

    

  Male

66

61

65

63

  Female

48

54

48

53

Age group, years, n

    

  18-44

106

101

100a

99

  45-64

8

13

13

15

  ≥65

0

1

0

2

  Mean (SD)

29.4 (9.6)

30.2 (11.0)

30.2 (11.0)

31.2 (12.4)

Weight, kg

    

  Mean (SD)

61.4 (10.8)

60.4 (11.0)

60.0 (9.9)

59.4 (10.1)

  Range

40.0-105.0

39.0-107.0

40.0-83.6

39.0-94.0

Baseline parasite count/μL, mean ± SD

20,889 ± 24,176

20,146 ± 27,564

16,686 ± 22,863

17,651 ± 22,435

  Range

160-111,040

1,040-164,600

120-93,440

1,000-97,234

Number of episodes of malaria in previous 2 years

    

  0

61

66

69

67

  1

20

18

9

14

  2

15

9

16

18

  ≥3

17

22

19

17

  1. aOne subject <18 years of age.
  2. AZCQ 1,000 mg, azithromycin 1,000 mg plus chloroquine 600-mg base; MQ, mefloquine hydrochloride; SD, standard deviation.