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Table 4 Number of subjects with pfcrt gene mutations in study 1134

From: Efficacy and safety of a combination of azithromycin and chloroquine for the treatment of uncomplicated Plasmodium falciparum malaria in two multi-country randomised clinical trials in African adults

 

AZCQ 1,000 mg (N = 114)

MQ 1,250 mg (N = 114)

CQ-sensitive, n

48

59

  CVMNK

48

58

  SVMNK

0

1

CQ-resistant, n

63

52

  CVMET

0

1

  CVMNT

9

6

  CVIET

54

45

Negative, n

3

2

Other, n

0

1

  1. AZCQ 1,000 mg, azithromycin 1,000 mg plus chloroquine 600-mg base; CQ, chloroquine; MQ, mefloquine hydrochloride; pfcrt, Plasmodium falciparum CQ resistance transporter gene.