Molecule | Cytotoxicity* MLD 50 (μM) | SI(MLD 50 /IC 50 ) | |
---|---|---|---|
HepG2 cells | W2 (CQ-R) | 3D7 (CQ-S) | |
CQAn28 | 1508.56 ± 344.50 | 2125 | 101 |
CQAn33 | 152.89 ± 12.86 | 7645 | 131 |
CQAn34 | 943.29 ± 73.15 | 4101 | 3144 |
CQAn37 | 1699.24 ± 10.07 | 24275 | 2981 |
CQAn39 | ≥3207.08 | 5011 | 1342 |
CQAn45 | 1015.84 ± 42.97 | 1319 | 868 |
Chloroquine | 410.4±26.6 | 1080 | 5,679 |