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Table 4 Inhibitory concentrations of β-haematin formation by chloroquine (CQ) and two analogs (CQAn)*

From: Antiplasmodial activity of chloroquine analogs against chloroquine-resistant parasites, docking studies and mechanisms of drug action

CQAn

Exp

Mean ± SD

1

2

3

33

4.7

3.0

5.6

4.3 ± 1.3

37

2.7

10.2

7.5

8.9 ± 3.8

CQ

0.6

2.0

5.0

3.5 ± 2.2

  1. *Results expressed as IC50 in mM.
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Malaria Journal

ISSN: 1475-2875

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