Circulating antibodies against Plasmodium falciparum histidine-rich proteins 2 interfere with antigen detection by rapid diagnostic tests

Table 1 Demographics and parasitaemia of the plasma samples

Sample type	Country	n	Age		Parasitemia
Sample type	Country	n	Median	(Range)	Geometric mean	(Range)
Acute patients (symptomatic & microscopy + ve)	Cambodia	15	21	(8–51)	20,940	(2,005-195,665)
	Nigeria	23	23	(9–37)	18,528	(5,118-142,696)
	Philippines	37	19	(4–71)	1,767	(30–79,821)
Asymptomatic (microscopy + ve or –ve)	Solomon Islands	28	*29	(13–66)	11 were microscopy positive for P. falciparum with low densities
Uninfected endemic controls	Nigeria	10	Unknown		N/A
Uninfected endemic controls	Philippines	8	28	(7–76)	N/A
Non-exposed control	Brisbane	6	Unknown		N/A

*Calculated based on information available from 17 subjects. An additional five subjects were adults, and six subjects had unknown age.

ISSN: 1475-2875