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Figure 10 | Malaria Journal

Figure 10

From: Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria

Figure 10

Proposed approximate dose-response relationships for primaquine in falciparum malaria. Approximate dose-response relationships in falciparum malaria for primaquine inhibition of infectiousness (blue dashed curve) presumably reflecting susceptibility of male gametocytes, and effects on gametocyte clearance (pink dashed curve) reflecting susceptibility of female gametocytes. Arrow shows currently recommended transmission-blocking primaquine dose of 0.25 mg/kg. Studies are in progress to characterize these relationships more accurately.

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