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Table 2 (A-D): Calculation of the 6 month cumulative attack rate ( Pf , Pv , all species) and Pf to Pv ratio during the 1999/00 ADF deployment

From: A retrospective analysis of the protective efficacy of tafenoquine and mefloquine as prophylactic anti-malarials in non-immune individuals during deployment to a malaria-endemic area

A: Cumulative attack rates (%) by time period, species and battalion exposed during the 1999/2000 ADF deployment*
Time period (months)/(Battalions deployed) Species 2RAR (n = 681) 3RAR (n = 634) 5/7RAR (n = 522)
Period 1: Oct 25 99-Oct 31 00 (0.2)/(2RAR and 3RAR) Pv/Pf/All species 0.41/0.06/0.47 0.44/0.07/0.52 NA/NA/NA
Period 2: Nov 1 99-Jan 31 00 (3.0)/(2RAR, 3RAR and 5/7 RAR) Pv/Pf/All species 6.10/0.92/7.02 6.56/0.98/7.76 2.52/0.34/2.95
Period 3: Feb 1 00 – April 25 00 (2.8)/(5/7RAR) Pv/Pf/All species NA/NA/NA NA/NA/NA 2.38/0.32/2.78
B: Estimate of overall cumulative attack rate (%) by period for ALL battalions exposed during the 1999/2000 ADF deployment*
Time period (months) Species Cumulative attacks for all battalions
Period 1: Oct 25 99-Oct 31 99 (0.2) Pv/Pf/All species 0.42/0.06/0.49
Period 2: Nov 1 99-Jan 31–00 (3.0) Pv/Pf/All species 5.24/0.77/6.12
Period 3: Feb 1 00 – April 25 00 (2.8) Pv/Pf/All species 2.38/0.32/2.78
C: Estimate of the 6 month cumulative attack rate for battalions exposed during the 1999/00 ADF deployment**
Time period (months) Species Cumulative attack rates for all battalions
Periods 1, 2 and 3:Oct 25 99-April 25 00 (6.0) Pv/Pf/All species 7.89/1.15/9.18
D: Estimate of Pf to Pv ratio for all battalions exposed during the 1999/00 ADF deployment*** 0.146 (1.15/7.89)
  1. *Overall attack rates are the weighted averages of attack rates for battalions exposed during the period (weights = sample size).
  2. **Cumulative attack rate (probability) = P1 + (1-P1)*P2 + (1-P1)(1-P2)*P3 where P1, P2 and P3 are the estimated overall attack rates for periods 1, 2 and 3 (from Table 2B).
  3. ***Cumulative Pf attack for all battalions (from Table 2C)/Cumulative Pv attack rate for all battalions (from Table 2C).