From: Composite endpoints for malaria case-management: not simplifying the picture?
 | True status |  | ||
---|---|---|---|---|
How managed | Positive | Negative | Total | |
 | Treated | a | c | a+c |
 | Not treated | b | d | b+d |
 | Total | a+b | c+d | N |
Prevalence | (a+b)/N | |||
Positive management rate (PMR) | a/(a+b) | |||
Negative management rate (NMR) | d/(c+d) | |||
Combined management rate (CMR) | (a+d)/N | OR | ||
 | PMR*p+NMR*(1-p) | |||
Predictive values | Â | |||
% positive among treated | a/(a+c) | |||
% negative among not treated | d/(b+d) |