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Table 3 Average number of pvmsp-7 gene synonymous substitutions per synonymous site (d S ) and non-synonymous substitutions per non-synonymous site (d N )

From: Heterogeneous genetic diversity pattern in Plasmodium vivax genes encoding merozoite surface proteins (MSP) -7E, −7F and -7L

n Gene 5′-end Central 3′-end Full-length gene
Worldwide isolates dS(SE) dN(SE) dS(SE) dN(SE) dS(SE) dN(SE) dS(SE) dN(SE)
35 msp-7E 0.0488 (0.0118)• 0.0082 (0.0032) 0.0717 (0.0163) 0.1573 (0.0134)• 0.0665 (0.0130)• 0.0171 (0.0045) 0.0626 (0.0078) 0.0551 (0.0055)
41 msp-7F 0.0000 (0.0000) 0.0000 (0.0000) 0.0000 (0.0000) 0.0013 (0.0012) 0.0000 (0.0000) 0.0018 (0.0018) 0.0000 (0.0000) 0.0011 (0.0007)^
36 msp-7L 0.0006 (0.0005) 0.0000 (0.0000) 0.0000 (0.0000) 0.0012 (0.0008) 0.0013 (0.0012) 0.0008 (0.0008) 0.0006 (0.0005) 0.0007 (0.0004)
Colombian isolates         
31 msp-7E 0.0473 (0.0115)• 0.0079 (0.0032) 0.0706 (0.0168) 0.1549 (0.0135)• 0.0633 (0.0124)• 0.0161 (0.0042) 0.0606 (0.0077) 0.0539 (0.0056)
36 msp-7F 0.0000 (0.0000) 0.0000 (0.0000) 0.0000 (0.0000) 0.0012 (0.0011) 0.0000 (0.0000) 0.0017 (0.0016) 0.0000 (0.0000) 0.0010 (0.0007)^
31 msp-7L 0.0000 (0.0000) 0.0000 (0.0000) 0.0000 (0.0000) 0.0012 (0.0009) 0.0010 (0.0010) 0.0009 (0.0008) 0.0004 (0.0004) 0.0007 (0.0004)
  1. SE: standard error. 5′-end (pvmsp-7E: nucleotide 1–390, pvmsp-7F: nucleotide 1–432, pvmsp-7L: nucleotide 1–381), central (pvmsp-7E: nucleotide 391–747, pvmsp-7F: nucleotide 433–1,053, pvmsp-7L: nucleotide 382–816) and 3′-end (pvmsp-7E: nucleotide 748–1,158, pvmsp-7F: nucleotide 1,054–1,449, pvmsp-7L: nucleotide 817–1,275). Numbering based on Additional files4,9 and10. ^: p = 0.06, •: p <0.001.