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Table 4 Average number of msp-7 gene synonymous divergence per synonymous site (K S ) and non-synonymous divergence per non-synonymous site (K N )

From: Heterogeneous genetic diversity pattern in Plasmodium vivax genes encoding merozoite surface proteins (MSP) -7E, −7F and -7L

n Gene 5′ end Central 3′ end Full-length gene
Worldwide isolates KS(SE) KN(SE) KS(SE) KN(SE) KS(SE) KN(SE) KS(SE) KN(SE)
36 msp-7E 0.0746 (0.0156)• 0.0126 (0.0034) 0.0813 (0.0185) 0.1976 (0.0191)• 0.0980 (0.0163)• 0.0299 (0.0056) 0.0833 (0.0092) 0.0676 (0.0066)
42 msp-7F 0.0098 (0.0023)† 0.0047 (0.0009) 0.0146 (0.0029) 0.0141 (0.0022) 0.0086 (0.0022) 0.0100 (0.0022) 0.0110 (0.0014) 0.0096 (0.0010)
37 msp-7L 0.0140 (0.0031)‡ 0.0092 (0.0017) 0.0172 (0.0035) 0.0149 (0.0020) 0.0111 (0.0025)‡ 0.0070 (0.0013) 0.0139 (0.0017)* 0.0102 (0.0010)
Colombian isolates         
32 msp-7E 0.0755 (0.0151)• 0.0128 (0.0032) 0.0808 (0.0183) 0.1963 (0.0191)• 0.0982 (0.0156)• 0.0305 (0.0053) 0.0834 (0.0089) 0.0676 (0.0065)
37 msp-7F 0.0111 (0.0027)† 0.0053 (0.0011) 0.0165 (0.0033) 0.0156 (0.0023) 0.0098 (0.0025) 0.0110 (0.0022) 0.0125 (0.0016) 0.0107 (0.0011)
32 msp-7L 0.0156 (0.0037)‡ 0.0107 (0.0020) 0.0199 (0.0041) 0.0170 (0.0023) 0.0123 (0.0027)‡ 0.0081 (0.0015) 0.0157 (0.0019)* 0.0118 (0.0011)
  1. SE: standard error. 5′-end (pvmsp-7E: nucleotide 1–390, pvmsp-7F: nucleotide 1–432, pvmsp-7L: nucleotide 1–381), central (pvmsp-7E: nucleotide 391–747, pvmsp-7F: nucleotide 433–1,053, pvmsp-7L: nucleotide 382–816) and 3′-end (pvmsp-7E: nucleotide 748–1,158, pvmsp-7F: nucleotide 1,054–1,449, pvmsp-7L: nucleotide 817–1,275). Numbering based on Additional files4,9 and10. ‡: p <0.09, *: p <0.04, †: p <0.02, •: p <0.001.