Table 4 Summary of mean (standard deviation) and mean changes in haematological and biochemical data

Haematology

 Haemoglobin (g/dL)

13.4 (2.1)

12.0 (1.8)

12.6 (1.8)

−1.4

<0.000

−0.8

<0.000

 White blood cells*

5.4 (1.4)

6.3 (1.9)

5.6 (2.3)

0.9

0.0012

0.3

0.44

 Neutrophils*

3.1 (1.4)

2.6 (1.1)

2.2 (1.5)

−0.4

0.046

−0.9

0.00046

 Lymphocytes*

1.3 (0.6)

2.6 (0.9)

2.4 (0.9)

1.2

<0.000

1.0

<0.0000

 Monocytes*

0.71 (0.28)

0.66 (0.26)

0.48 (0.24)

−0.05

0.25

−0.22

<0.000

 Eosinophils*

0.13 (0.16)

0.37 (0.43)

0.41 (0.47)

0.24

<0.000

0.28

<0.0000

 Platelets*^†

96.0 (18–254)

234 (187–311)

175 (140–213)

126.0

<0.000

81.0

<0.0000

Biochemistry

 AST^¶ (U/L)

32.9 (13.2)

33.0 (18.7)

28.3 (11.0)

1.1

0.68

−4.4

0.0268

 ALT^¶ (U/L)

29.5 (21.8)

33.8 (20.8)

22.0 (10.2)

5.7

0.03

−8.1

0.005

 Total bilirubin^‡

16.9 (14.8)

7.2 (7.9)

7.0 (6.6)

−10.0

<0.000

−9.4

0.00014

 Creatinine^‡

73.5 (20.3)

71.8 (17.6)

71.9 (27.4)

−2.3

0.50

−3.4

0.48