Figure 1
From: Enantioselective metabolism of primaquine by human CYP2D6
Concentration- and time-dependent metabolism of primaquine and its enantiomers. (A) Steady state kinetics of primaquine and its enantiomers – a profile of the initial rate of substrate depletion (V o ) against concentration and (B) comparative depletion of primaquine and its enantiomers from human CYP2D6 incubation over 2 hr. Each point represents mean values ± S.D. (n = 4).