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Table 2 Rapid diagnostic test results from frozen Plasmodium knowlesi blood samples

From: Evaluation of three rapid diagnostic tests for the detection of human infections with Plasmodium knowlesi

P. knowlesi parasitaemia (parasites/μl)

OptiMAL-IT

BinaxNOW® Malaria

Paramax-3

  

Number of samples tested

 

Number of samples tested

 

Number of samples tested

>5,000

Pf-positive (Pf and Pan-positive)

8

Pf-positive

0

Pf-positive (Pf and Pan-positive)

0

Pan-positive (Pv/Pm/Po) only

0

Pan-positive (Pv/Pm/Po) only

5

Pv-positive (Pv and Pan-positive)

7

Pan-positive (Pm/Po) only

0

Negative

0

Negative

3

Negative

1

1,001-5,000

Pf-positive (Pf and Pan-positive)

12

Pf-positive

0

Pf-positive (Pf and Pan-positive)

0

Pan-positive (Pv/Pm/Po) only

1

Pan-positive (Pv/Pm/Po) only

2

Pv-positive (Pv and Pan-positive)

4

Pan-positive (Pm/Po) only

0

Negative

0

Negative

11

Negative

9

501-1,000

Pf-positive (Pf and Pan-positive)

4

Pf-positive

0

Pf-positive (Pf and Pan-positive)

0

Pan-positive (Pv/Pm/Po) only

0

Pan-positive (Pv/Pm/Po) only

2

Pv-positive (Pv and Pan-positive)

1

Pan-positive (Pm/Po) only

0

Negative

4

Negative

6

Negative

7

1-500

Pf-positive (Pf and Pan-positive)

4

Pf-positive

0

Pf-positive (Pf and Pan-positive)

0

Pan-positive (Pv/Pm/Po) only

1

Pan-positive (Pv/Pm/Po) only

1

Pv-positive (Pv and Pan-positive)

1

Pan-positive (Pm/Po) only

0

Negative

7

Negative

11

Negative

11

TOTAL

Pf-positive (Pf and Pan-positive)

28

Pf-positive

0

Pf-positive (Pf and Pan-positive)

0

Pan-positive (Pv/Pm/Po) only

2

Pan-positive (Pv/Pm/Po) only

10

Pv-positive (Pv and Pan-positive)

13

Pan-positive (Pm/Po) only

0

Negative

11

Negative

31

Negative

28

Total tested

 

41

 

41

 

41

Total positive

 

30

 

10

 

13

Sensitivity

 

73%

 

24%

 

32%

(95% CI)

 

(59 – 87%)

 

(11 – 37%)

 

(17 – 46%)