Table 1 In vitro susceptibility of Plasmodium falciparum isolates to anti-malarial drugs
Drug | IC50mean (nM) | IC99mean (nM) | Resistance threshold (nM) |
|---|---|---|---|
Chloroquine (CQ) | 24.4 | 164.2 | > 160 |
Amodiaquine (AQ) | 6.3 | 32.4 | > 80 |
Artesunate (AS) | 3.2 | 7.8 | > 10.5 |
Mefloquine (MQ) | 42.1 | 60.8 | > 64.0 |
Sulphadoxine/Pyrimethamine (SP) | 55.0 | 200 | > 300 |
0.7 | 2.5 | > 4.0 | |
Quinine (Q) | 60.3 | 298.6 | > 300 |