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Table 5 Prevalence of molecular markers associated with P . falciparum resistance to chloroquine

From: Plasmodium vivax and Plasmodium falciparum ex vivo susceptibility to anti-malarials and gene characterization in Rondônia, West Amazon, Brazil

Gene – codon % of mutations Mutations Protein change
PfMDR1    
86 0% - -
184 100% TAT > TTT Tyrosine > Phenylalanine
1034 84% AGT > TGT Serine > cysteine
1042 100% AAT > GAT Asparagine > Aspartic acid
1246 100% GAT > TAT Aspartic acid > Tyrosine
PfCRT    
72 100% AAA > ACA Lysine > Treonine
76 100% TGT > TCT Cysteine > Serine