Table 1 Summary of promising anti-malarial flavonoids derived from African flora
Compound subclass | Isolated metabolites | Plant species (Family) | Part of plant studied | Place of harvest (locality, country) | Author, reference |
|---|---|---|---|---|---|
Chalcones | 1 and 2 | Erythrina abyssinica (Leguminosae) | Stem bark | Thika town, Kenya | |
3 | Milletia usaramensis ssp. usaramensis (Leguminosae) | Stem bark | Jadini Forest, Kenya | Yenesew et al.[58] | |
4, 5 and 6 | Uvaria sp. (Annonaceae) | Leaves, stem and root bark | Tanzania | Nkunya et al.[59] | |
7 and 8 | Friesodielsia obovata (Annonaceae) | Root bark | Tabora district, Tanzania | Joseph et al.[60] | |
9, 10, 11, 12, 13, and 14 | Polygonum senegalense (Polygonaceae) | Aerial parts | Nairobi, Kenya | Midowo et al. [61] | |
4 and 15 | Uvaria puguensis (Annonaceae) | Stem bark | Pugu Forest Reserve, Tanzania | Makangara et al.[62] | |
16, 17, 18, and 19 | Dorstenia barteri (Moraceae) | Twigs | Tombel, Cameroon | Ngameni et al.[63] | |
Flavanones | 20, 21, 22, 23, 24, and 25 | Erythrina abyssinica (Leguminosae) | Stem bark | Thika town, Kenya | |
26 and 27 | Derris trifoliate (Leguminosae) | Seed pods | Coast Province, Kenya | Yenesew et al.[64] | |
28 and 29 | Polygonum senegalense (Polygonaceae) | Aerial parts | Nairobi, Kenya | Midowo et al. [61] | |
30 | Erythrina abyssinica (Leguminosae) | Stem bark | Thika town, Kenya | Yenesew et al.[57] | |
31 and 32 | Morus mesozygia (Moraceae) | Stem bark | Centre Province, Cameroon | Zelefack et al.[65] | |
Isoflavones | 33 | Ficus mucuso (Moraceae) | Figs | Tongolo-Yaoundé, Cameroon | Bankeu et al.[66] |
34 | Erythrina sacleuxii (Leguminosae) | Root bark | Kenya | Andayi et al.[67] | |
Retonoids | 35, 36, 37 and 38 | Milletia usaramensis ssp. usaramensis (Leguminosae) | Stem bark | Jadini Forest, Kenya | Yenesew et al.[58] |