Phenotypic characterization of Plasmodium berghei responsive CD8+ T cells after immunization with live sporozoites under chloroquine cover

Table 2 CD8+ T cells containing KLRG1 ^high , CD27 ^low phenotype

Group	Mean CD8+ KLRG1^high, CD27^lowcells (%)	95% CI of mean		Number of lymphocytes/ml × 10^3	Absolute number of CD + KLRG1^high, CD27^lowT cells × 10^3/ml of blood
		Lower	Upper
Control (15)	1.04	0.73	1.36	15,409	160.168
Post-3 (22)	5.72	4.41	7.04	14,894	841.32
Post-1 (5)	1.30	0.95	1.64	16,518	214.147

Infection/cure animals were inoculated three times (post-3) or one time with 20,000 Spz (post-1). The second column shows means of percent CD8+ cells expressing KLRG1^high, CD27^low phenotype in the circulating peripheral lymphocytes. Statistical significance was determined using Mann Whitney test. The numbers of animals used in each experiment per group are shown in brackets. There was significant difference between the control vs. post-3 groups (p < 0.0001) and between post-3 vs. post-1 (p = 0.0013). There was no significant difference between control vs. post-1 groups. The last two columns show the number of CD8+ KLRG1^high, CD27^low T cell × 10^3/ml of blood.

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