Phenotypic characterization of Plasmodium berghei responsive CD8+ T cells after immunization with live sporozoites under chloroquine cover

Table 3 Mean CD8+ KLRG1 ^high , CD27 ^low T cell (%) expressed in circulating peripheral blood of control, protected and non-protected animals

Twelve C57BL/6 mice were immunized twice with 20,000 Spz. Six mice were protected and six were not protected. Statistical significance was determined using Mann Whitney test. The numbers of animals used in each group are shown in brackets. There was significant difference between the control vs. protected groups (p = 0.024) and protected vs. non-protected (p = 0.0087). There was a marginal significant difference between control vs. non-protected (p = 0.0476).

ISSN: 1475-2875