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Table 1 Mean percentage of parasitaemia (± S.E.M) and percentage of parasite growth inhibition data of NP046 in P. berghei- infected male C57BL/6 mice, assessed on day five post-infection

From: Efficacy and pharmacokinetic evaluation of a novel anti-malarial compound (NP046) in a mouse model

Treatment

% parasitaemia

% growth inhibition

50 mg/kg NP046 oral

16.7 ± 3.34

47.3

10 mg/kg NP046 oral

24.3 ± 0.80

24.6

5 mg/kg NP046 IV

4.05 ± 0.12

87.4

1 mg/kg NP046 IV

10.2 ± 1.75

57.6

Positive control

0.01 ± 0.0

100

Negative control

32.2 ± 0.50

0