From: Efficacy and pharmacokinetic evaluation of a novel anti-malarial compound (NP046) in a mouse model
Treatment | % parasitaemia | % growth inhibition |
---|---|---|
50 mg/kg NP046 oral | 16.7 ± 3.34 | 47.3 |
10 mg/kg NP046 oral | 24.3 ± 0.80 | 24.6 |
5 mg/kg NP046 IV | 4.05 ± 0.12 | 87.4 |
1 mg/kg NP046 IV | 10.2 ± 1.75 | 57.6 |
Positive control | 0.01 ± 0.0 | 100 |
Negative control | 32.2 ± 0.50 | 0 |