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Table 1 Mean percentage of parasitaemia (± S.E.M) and percentage of parasite growth inhibition data of NP046 in P. berghei- infected male C57BL/6 mice, assessed on day five post-infection

From: Efficacy and pharmacokinetic evaluation of a novel anti-malarial compound (NP046) in a mouse model

Treatment % parasitaemia % growth inhibition
50 mg/kg NP046 oral 16.7 ± 3.34 47.3
10 mg/kg NP046 oral 24.3 ± 0.80 24.6
5 mg/kg NP046 IV 4.05 ± 0.12 87.4
1 mg/kg NP046 IV 10.2 ± 1.75 57.6
Positive control 0.01 ± 0.0 100
Negative control 32.2 ± 0.50 0