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Table 3 Detection (or rejection) of differentially expressed genes using various P-value correction methods.

From: Effect of sample size and P-value filtering techniques on the detection of transcriptional changes induced in rat neuroblastoma (NG108) cells by mefloquine

 

Fold-change > 2

P < 0.05

Reverse Holm Procedure

 

Holm-Bonferroni

No of ...

  

P < 0.05

P < 0.01

 

Significant genes

27

33

10

5

0

Differentially expressed genes detected1

7

7

7

5

0

Differentially expressed genes rejected1

0

0

0

2

7

  1. Notes 1. Altered expression of a gene was established using RT-PCR.