Figure 4

HO-1 staining of tissues from bacterial sepsis cases. A and B brain, C and D lung, and E and F liver. Case14 (A, C and E), an E. coli infection, demonstrates no brain monocyte activity (A), but pulmonary monocytes and macrophages (C), and Kupffer cells (E) stained strongly. While case 18 (B, D and F), a H. influenzae infection, had no HO-1 staining in the brain or lung, Kupffer cells stained strongly. Scale bar, 100 μm.