Table 2 3D7 loci with sequence similarity to var loci found in at least two of the three isolates described in this study. Sequences from isolates 1 or 2 which were found in at least one other isolate were compared to sequences in the genome of clone 3D7 using BLAST software at the PlasmoDb site. The number of times each sequence was identified in each isolate is shown in columns two to four. The 3D7 locus with the most similarity (i.e. lowest probability) is shown in each case.
From: Sympatric Plasmodium falciparum isolates from Venezuela have structured var gene repertoires
DBL sequence | Isolate | 3D7 Locus | Probabillity | var class | Orientation | ||
|---|---|---|---|---|---|---|---|
#1 | #2 | #3 | |||||
#1-01 | 3 | - | 1 | Chr 6: MAL6P1.316 | 5.0 × e-42 | Atypical Type 2 | Away from telomere |
#1-02 | 2 | - | 1 | Chr 6: MAL6P1.316 | 7.0 × e-38 | Atypical Type 2 | Away from telomere |
#1-05 | 3 | 1 | - | Chr 9: PFI1820 | 2.1 × e-37 | Atypical Type 3 | Towards telomere |
#1-08 | 7 | 5 | 3 | Chr 11: PF11_0521 | 3.0 × e-48 | Atypical Type 9 | Towards telomere |
#1-09 | 2 | - | 6 | Chr12: PFL0020 | 5.4 × e-38 | Type 1 | Away from telomere |
#1-14 | 1 | 2 | - | Chr 8: PF08_0106 | 2.2 × e-37 | Type 1 | Central cluster |
#1-22 | 19 | 1 | 3 | Chr 4: PFD1000 / PFD0995 | 7.1/7.4 × e-42 | Type 1 | Duplicated; central cluster |
#2-01 | - | 3 | 8 | Chr 8: PF08_0141 | 4.6 × e-46 | Atypical Type 2 | Towards telomere |