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Table 1 Human transcripts detected in P. falciparum infected patient blood samples and in vitro cultivated 3D7 samples Comparison of expression level of the most abundant human transcripts detected in in vivo blood and in 3D7 in vitro cultivated samples. Average expression level of in vivo isolated RNA derived from the average expression level of three samples from Senegal and one from Nigeria compared with the average expression level from three 3D7 ring stage in vitro isolated RNA samples. Transcripts are listed in order of highest abundance in vivo as detected by array. Expression levels are reported as expression units (EU), using the MOID algorithm.

From: In vivo transcriptional profiling of Plasmodium falciparum

  

Expression Units

Gene

Description

in vivo

in vitro 3D7

Hs.155376_at

haemoglobin, beta

757266

101307

Hs.36977_at

haemoglobin, delta EST, similar to tctp human translationally controlled tumor protein H. sapiens

395849

12265

Hs.203820_at

 

241506

6932

Hs.21295_at

EST, Weakly similar to KIAA0902 protein H. sapiens

190454

9321

Hs.247921_at

haemoglobin, theta 1

188961

4528

Hs.87246_at

Bcl-2 binding component 3

187575

5688

Hs.256047_at

ESTs, similar to B24264 proline-rich protein MP3 -M. musculus

160290

5681

Hs.14587_at

ESTs, similar to AF1 51 859_1 CGI-101 protein H. sapiens

155768

6389

Hs.117848_at

haemoglobin, epsilon 1

150921

5903

Hs.168073_at

DKFZP727M231 protein

147492

6615

Hs.24545_at

hypothetical protein FLJ11137

146324

6292

Hs.6318_at

peroxisomal short-chain alcohol dehydrogenase

145846

5136

Hs.155833_at

ESTs, similar to spliceosomal protein SAP 155 H. sapiens Homo sapiens mRNA; cDNA DKFZp434H0820 (from clone DKFZp434H0820); partial cds

140563

5508

Hs.109857_at

 

138856

7397

Hs.248677_at

ESTs, similar to A48018 mucin 7 precursor, salivary – H. sapiens

136390

5253

Hs.4205_at

hypothetical protein FLJ20124 ATPase, H+ transporting, lysosomal (vacuolar proton pump), member D

132244

4050

Hs.106876_at

 

127582

3930

Hs.172914_at

retinol dehydrogenase 5 (11-cisand 9-cis)

125310

4560

Hs.23898 at

paraneoplastic antigen

124648

5631