Table 2 P. falciparum genes expressed in vivo encoded by chromosome 2. In vivo transcripts from the Nigerian sample were defined as present as compared to uninfected blood control hybridization. Asterisk (*) denotes transcripts that were also detected in a Senegal derived blood sample. Genes in bold are uniquely expressed in vivo and were not found to be expressed in the previously reported 3D7 ring stage transcriptome. Gene locus is from PlasmoDB 4.1 http://plasmodb.org/.
From: In vivo transcriptional profiling of Plasmodium falciparum
gene locus | description | gene locus | description |
|---|---|---|---|
membrane proteins | cellular function | ||
PFB0120w* | etramps 2 | PFB0175c* | prt of the MAK16 family |
PFB0405w* | transmission blocking target antigen | PFB0205c | prt with 5'-3' exonucl. domain |
PFB0015c | rifin | PFB0210c | monosaccharide transporter |
PFB0025c | rifin | PFB0265c* | RAD2 endonucl. |
PFB0035c | rifin | PFB0295w* | adenylosuccinate lyase (OO) |
PFB1010w* | rifin | PFB0380c | phosphatase (acid phosphatase family) |
PFB1020w* | rifin | PFB0390w* | ribosome releasing factor (OO, TP) |
PFB1035w* | rifin | PFB0410c* | phospholipase A2-like a/b fold hydrolase |
PFB1050w* | rifin | PFB0445c | elF-4A-like DEAD family RNA helicase |
PFB0330c | SERA antigen/papain-like protease | PFB0510w | GAF domain prt |
PFB0340c | SERA antigen/papain-like protease | PFB0525w | asparaginyl-tRNA synthetase (OO, TP) |
PFB0345c* | SERA antigen/papain-like protease | PFB0585w | Leu/Phe-tRNA prt transferase |
PFB0355c* | SERA antigen/papain-like protease | PFB0595w* | prt with DnaJ domain, DNJ1/SIS1 family |
PFB0360c | SERA antigen/papain-like protease | PFB0760w | Mtn3/RAG1IP-like prt |
PFB0095c | membrane protein, PfEMP3 | PFB0795w | ATP synthase alpha chain |
PFB0975c | PfEMP1 fragment | PFB0815w* | calcium-dept. prt kinase |
PFB1045w | Pf EMP1 fragment | PFB0875c | chromatin-binding prt (SKI/SNW family) |
PFB1055c | PfEMP1 (var gene) | hypothetical proteins | Â |
PFB0085c* | prt with DnaJ domain (RESA-like) | PFB0135c | hypothetical protein |
PFB0100c* | knob-associated His-rich prt | PFB0490c* | hypothetical protein |
PFB0300c | merozoite surface antigen MSP-2 | PFB0575c | hypothetical protein |
PFB0475c | predicted multiple-TM membrane prt | PFB0580w | hypothetical protein |
PFB0770c* | predicted multiple-TM membrane prt | PFB0630c | hypothetical protein |
PFB0125c | predicted membrane associated prt | PFB0705w | hypothetical protein |
PFB0735c | predicted integral membrane protein | PFB0745w | hypothetical protein |
PFB0275w* | membrane transporter | PFB0870w | hypothetical protein |
PFB0465c | membrane transporter | other | Â |
| Â | Â | PFB0675w | predicted secreted protein |
| Â | Â | PFB0990c | predicted secreted protein |