Table 2 Descriptive adverse event data from Barennes [30]
From: Intrarectal quinine for treating Plasmodium falciparum malaria: a systematic review
Adverse event | Intrarectal (number affected/total number of patients, %) | Intramuscular (number affected/total number of patients, %) |
|---|---|---|
Liquid stool (<3/day) | 109/450 (24.2) | 7/448 (1.5) |
Mucoid stools | 296/450 (65.7) | 23/448 (5.10) |
Blood in stool | 20/450 (4.4) | 3/448 (0.7) |
Painful contractions | 64/450 (14.2) | No data |
Inflammation at the injection site | No data | 358/448 (80) |
Tenesmus | 56/450 (12.4) | No data |
Number investigated by anoscopy with a single microulceration healing within 24 hours | 4/259 (1.5) | No data |
Multiple microulcerations recovering by day 7 | 1/259 (0.4) | No data |
Difficulty in walking | No data | 67/448 (15) |
Sciatic paresthesia | No data | 1/448 (0.2) |
Fever recurrence due to inflammation or infection of the injection site | No data | 30/448 (6.6) |